논문 국내 국제일반학술지 Inhibition of electric eel acetylcholinesterase by porphin compounds
- 학술지 구분 국제일반학술지
- 게재년월 2016-10
- 저자명 이봉호공동(교신)
- 학술지명 Bioorganic & Medicinal Chemistry Lett
- 발행처명 Elsevier
- 발행국가 국내
- 논문언어 한국어
홈페이지논문 초록 (Abstract)
Synthetic porphin compounds have been found to be reversible inhibitors of acetylcholinesterase from electric eel with Ki values of μ M range. It seems that the number and position of fluorine on the phenyl ring and metal of an inhibitor play an important role for binding of an inhibitor to the enzyme active site. Synthetic porphin compounds have been found to be reversible inhibitors of acetylcholinesterase from electric eel with Ki values of μM range. It seems that the number and position of fluorine on the phenyl ring and metal of an inhibitor play an important role for binding of an inhibitor to the enzyme active site.