논문 해외 국제전문학술지(SCI급) Meroditerpenoids from the Brown Alga Sargassum siliquastrum
- 학술지 구분 국제전문학술지(SCI급)
- 게재년월 2008-10
- 저자명 최병욱,이봉호공동(참여)
- 학술지명 JOURNAL OF NATURAL PRODUCTS
- 발행처명 AMER CHEMICAL SOC
- 발행국가 해외
- 논문언어 외국어
홈페이지논문 초록 (Abstract)
Eleven new meroditerpenoids (7−11, 14−17, 19, 20) and nine known compounds (1−6, 12, 13, 18) were isolated from the brown alga Sargassum siliquastrum. Combined chemical and spectroscopic analyses revealed a common tetraprenyl hydroquinone structure; these compounds belonged to the nahocol, isonahocol, and sargahydroquinoic acid classes. The dihydroquinone moiety of 20 was unique and unprecedented in a brown alga. Stereochemical assignments were made for several of the known compounds based on their chemical reactivity. These compounds exhibited moderate to significant radical-scavenging activity as well as weak inhibitory activities against sortase A and isocitrate lyase.