논문 해외 국제전문학술지(SCI급) Monoglycerides from the brown alga Saragssum sagamianum: Isolation, Synthesis, and biological Activity
- 학술지 구분 국제전문학술지(SCI급)
- 게재년월 2008-06
- 저자명 이봉호공동(참여),최병욱
- 학술지명 Bioorganic and Med. Chem. Lett.
- 발행처명 PERGAMON-ELSEVIER SCIENCE LTD
- 발행국가 해외
- 논문언어 외국어
홈페이지논문 초록 (Abstract)
Polyunsaturated fatty acid-derived monoglycerides were characterized from the marine brown alga Sargassum sagamianum, collected from Jeju Island, Korea. A new compound of this structural class was isolated and determined to be 1-octadecatetraenoyl glycerol, by combined spectroscopic methods. Based on the structures and bioactivity of these compounds, a series of monoglycerides were synthesized using glycerol and various fatty acids. Several compounds exhibited moderate to significant inhibition of phospholipase A(2) and cyclooxygenase-2.