논문 해외 국제전문학술지(SCI급) Development of three-dimensional haptotaxis model for single crawling cell
- 학술지 구분 국제전문학술지(SCI급)
- 게재년월 2010-09
- 저자명 송지환
- 학술지명 BIOCHIP JOURNAL
- 발행처명 SPRINGER
- 발행국가 해외
- 논문언어 외국어
- 전체저자수 2
홈페이지논문 초록 (Abstract)
This paper proposes a three-dimensional diffuse interface dynamic model with multiple mechanisms and confirms the high possibility of adequate predictions. In particular, we consider the nucleus that exhibits three-dimensional motion in the crawling cell, which enables a more realistic representation of haptotactic migration. A diffuse interface model that incorporates the haptotaxis mechanism and interface energies is employed. The semi-implicit Fourier spectral scheme is adopted for efficient evaluation of the simulation model. The simulation results confirm the reliability of the developed model.