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RESEARCH COMMUNICATION PORTAL

논문 해외 국제전문학술지(SCI급) A study on cancer-cell invasion based on multi-physics analysis technology

  • 학술지 구분 국제전문학술지(SCI급)
  • 게재년월 2010-06
  • 저자명 송지환
  • 학술지명 BIOCHIP JOURNAL
  • 발행처명 SPRINGER
  • 발행국가 해외
  • 논문언어 외국어
  • 전체저자수 3

논문 초록 (Abstract)

In this paper, a three-dimensional haptotaxis model to simulate the migration of a population of cancer cells has been proposed. The invasion of cancer cells is related with the hapto-attractant and the effect of the interface energies between the cells and the ECM. The diffuse interface model, which incorporates the haptotaxis mechanism and interface energies, is employed. The semi-implicit Fourier spectral scheme is adopted for efficient evaluation of the simulation. The simulation results thoroughly reveal the dynamics of cancer-cell migration.