논문 해외 국제전문학술지(SCI급) Nanoplasmonic Sensor Chip Readable in a Conventional Plate Reader
- 학술지 구분 국제전문학술지(SCI급)
- 게재년월 2022-05
- 저자명 정중희, 위정섭, 나희경, 유창혁, 최준규, 종지
- 학술지명 BioChip
- 발행처명 Springer
- 발행국가 해외
- 논문언어 외국어
홈페이지논문 초록 (Abstract)
In this report, we present a straightforward method for bridging a nanoplasmonic sensor with a conventional plate reader. By attaching lithographically prepared plasmonic nanostructures to a commercially available microwell strip, which has a perforated bottom, we could measure highly sensitive optical signals of plasmonic nanostructures using a conventional plate reader. The absorbance measurements and electromagnetic simulations show that a proper alignment between light polarization and the plasmonic nanostructure improves the sensing performance, which can be achieved with a linear polarizing film. Furthermore, the multiplexed detection capability of the proposed nanoplasmonic sensor chip was successfully demonstrated by monitoring four different enzyme–substrate reactions. These results illustrate the potential of the proposed nanoplasmonic sensor chip, which can combine advanced nanoplasmonic sensors with the well-developed microwell plate reader.