논문 해외 국제전문학술지(SCI급) Flexible chemical sensors using signal generation from cyclodextrin-analyte interactions on polymer composites
- 학술지 구분 국제전문학술지(SCI급)
- 게재년월 2020-09
- 저자명 Joonwon Bae, Dong-Sik Shin, Ji-Hwan Ha, Yunjung Hwang, Chang-Soo Lee, Hye Jun Kim, Ayeon Jang, Sung-Hoon Park
- 학술지명 BioChip Journal
- 발행국가 해외
- 논문언어 외국어
- 원문 링크 https://link.springer.com/article/10.1007/s13206-020-4303-3
홈페이지논문 초록 (Abstract)
We present the design of a chemical sensor and study the generation of electrical signals produced by the formation of a cyclodextrin inclusion complex. Flexible poly(dimethylsiloxane)/graphene hybrid composites were used as sensor substrates and sensing media, beta-cyclodextrin (beta-CD) molecules were incorporated using simple bio-coupling reactions. The feasibility of sensing molecules through the formation of beta-CD/analyte inclusion complexes was investigated systematically using direct electrical measurement. The acquisition and transduction of electrical signals generated by inclusion complex formation is a central focus of this study and extensive complementary experiments were carried out to characterize this phenomenon. Because it is useful for development of a sort of sensor system, electrical measurements were performed to measure the sensitivity of this system (10 nM). However, more study is required to determine the selectivity. This article will be a useful reference for the design of versatile chemical sensors utilizing a non-toxic sensing medium on flexible composite substrates.