논문 해외 국제전문학술지(SCI급) Analysis on improvement in resolution by excitation beam modulation in stimulated emission depletion nanoscopy
- 학술지 구분 국제전문학술지(SCI급)
- 게재년월 2019-10
- 저자명 김완진,임건,박노철
- 학술지명 OPTICAL REVIEW
- 발행처명 OPTICAL SOC JAPAN
- 발행국가 해외
- 논문언어 외국어
- 전체저자수 3
홈페이지논문 초록 (Abstract)
CW STED nanoscopy using illumination of continuous wave is considerably easy and less expensive to construct compared with the pulsed STED nanoscopy. In this study, to improve the resolution of CW STED nanoscopy, we analyzed the imaging characteristics of CW STED nanoscopy by amplitude modulation of incident light flux of the excitation beam illumination considering the polarization state and geometry of the pupil mask for amplitude modulation. We analyzed the imaging characteristics of STED nanoscopy by applying the characteristic, which shows an extremely confined electric field in transverse direction when the light waves with high spatial frequencies and with the same polarization direction are diffracted and interfered in the focal region. By applying linearly polarized illumination and the mixed-shaped aperture composed of the bow tie-shaped blocking area and the circular blocking aperture area, we analyzed that imaging resolution can be enhanced above 20% higher than the resolution of the conventional CW STED nanoscopy.